Clinical assessment of primalan (mequitasine) in allergology

Clinical assessment of primalan (mequitasine) in allergology

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Aim.To study efficacy of primalan (mequitasine) in the treatment of allergic rhinoconjunctivitis and chronic recurrent urticaria.Material and methods.The study COLD included 140 patients.Of them, 60 patients had allergic rhinitis, 80 patients had chronic recurrent urticaria.

All the patients received primalan (mequitasin) in a dose 10 mg/day (5 mg twice daily or a single dose 10 mg).The disease symptoms and side effects of primalan were assessed for 28 days of the treatment.Results.Primalan (mequitasin) proved to be highly effective against allergic rhinitis (good and very good response - 76%, satisfactory - 20%) and chronic recurrent urticaria (the response in 90% patients).Good primalan tolerance was reported.

Side effects were moderate and did not require the Flag drug withdrawal (sleepiness in 6.6%, dryness of the mucosa in 5%).Conclusion.Primalan (mequitasin) can be recommended for wide application in therapy of allergic rhinitis and chronic recurrent urticaria.